Sacha Gnjatic Selected Research

Testicular Neoplasms (Testicular Cancer)

7/2021	Randomized phase II trial of a first-in-human cancer cell lysate vaccine in patients with thoracic malignancies.
10/2019	First-in-Class, First-in-Human Study Evaluating LV305, a Dendritic-Cell Tropic Lentiviral Vector, in Sarcoma and Other Solid Tumors Expressing NY-ESO-1.
10/2017	First-in-Human Treatment With a Dendritic Cell-targeting Lentiviral Vector-expressing NY-ESO-1, LV305, Induces Deep, Durable Response in Refractory Metastatic Synovial Sarcoma Patient.
1/2017	NY-ESO-1 expression predicts an aggressive phenotype of ovarian cancer.
1/2016	HLA superfamily assignment is a predictor of immune response to cancer testis antigens and survival in ovarian cancer.
1/2016	Expression and clinical significance of MAGE and NY-ESO-1 cancer-testis antigens in adenoid cystic carcinoma of the head and neck.
3/2015	Resiquimod as an immunologic adjuvant for NY-ESO-1 protein vaccination in patients with high-risk melanoma.
6/2014	Cancer-testis antigen 7 expression and immune responses following allogeneic stem cell transplantation for multiple myeloma.
1/2014	Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer.
1/2014	Expression and immune responses to MAGE antigens predict survival in epithelial ovarian cancer.

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Sacha Gnjatic Research Topics

Disease

120	Neoplasms (Cancer) 01/2022 - 08/2002
56	Testicular Neoplasms (Testicular Cancer) 07/2021 - 12/2002
30	Melanoma (Melanoma, Malignant) 01/2021 - 12/2006
15	COVID-19 06/2022 - 01/2020
13	Ovarian Neoplasms (Ovarian Cancer) 07/2020 - 09/2003
11	Ovarian Epithelial Carcinoma 01/2016 - 09/2003
8	Inflammation (Inflammations) 01/2022 - 04/2016
7	Multiple Myeloma 01/2020 - 02/2007
5	Disease Progression 01/2022 - 01/2013
5	Lung Neoplasms (Lung Cancer) 07/2021 - 03/2004
5	Neoplasm Metastasis (Metastasis) 02/2017 - 09/2011
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2018 - 03/2004
3	Fatigue 01/2022 - 12/2012
3	Crohn Disease (Crohn's Disease) 01/2022 - 10/2016
3	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021 - 12/2003
3	Hypoxia (Hypoxemia) 10/2020 - 01/2017
3	Lymphoma (Lymphomas) 01/2019 - 02/2006
3	Synovial Sarcoma (Synovioma) 10/2017 - 01/2006
3	Prostatic Neoplasms (Prostate Cancer) 11/2013 - 07/2003
3	Esophageal Neoplasms (Esophageal Cancer) 04/2013 - 10/2004
3	Hypersensitivity (Allergy) 01/2013 - 07/2004
3	Fowlpox 04/2012 - 07/2003
3	Colorectal Neoplasms (Colorectal Cancer) 09/2011 - 09/2006
2	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 10/2004
2	Leukemia 10/2021 - 03/2012
2	Tetanus 01/2021 - 01/2012
2	Agammaglobulinemia (Hypogammaglobulinemia) 06/2020 - 01/2020
2	Pancreatic Neoplasms (Pancreatic Cancer) 11/2017 - 03/2010
2	Communicable Diseases (Infectious Diseases) 11/2017 - 12/2011
2	Lymphatic Metastasis 02/2017 - 07/2003
2	Esophageal Squamous Cell Carcinoma 01/2016 - 10/2004
2	Injection Site Reaction 12/2012 - 11/2008
2	Vaccinia 04/2012 - 09/2006
1	Multiple Sclerosis 06/2022
1	Constipation 01/2022
1	Necrosis 01/2022
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021
1	Cytokine Release Syndrome 01/2021

Drug/Important Bio-Agent (IBA)

88	AntigensIBA 07/2021 - 08/2002
36	Proteins (Proteins, Gene)FDA Link 07/2021 - 09/2002
34	VaccinesIBA 06/2022 - 09/2002
25	Peptides (Polypeptides)IBA 01/2021 - 08/2002
20	Neoplasm Antigens (Tumor Antigens)IBA 07/2020 - 03/2004
18	Biomarkers (Surrogate Marker)IBA 10/2021 - 02/2009
16	AntibodiesIBA 01/2022 - 08/2002
16	CytokinesIBA 01/2022 - 06/2008
13	EpitopesIBA 07/2020 - 09/2002
11	Messenger RNA (mRNA)IBA 01/2022 - 07/2003
10	IpilimumabIBA 10/2021 - 12/2008
9	Monoclonal AntibodiesIBA 01/2021 - 12/2008
9	Cancer VaccinesIBA 04/2012 - 03/2004
7	Interleukin-6 (Interleukin 6)IBA 10/2021 - 04/2010
6	AutoantibodiesIBA 01/2022 - 01/2009
6	Pharmaceutical PreparationsIBA 01/2022 - 12/2014
5	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2018
5	Recombinant ProteinsIBA 11/2020 - 03/2004
4	Immunoglobulin G (IgG)IBA 01/2022 - 03/2010
4	Antigen-Antibody Complex (Immune Complex)IBA 01/2022 - 09/2002
4	Interleukin-8 (Interleukin 8)IBA 10/2021 - 05/2020
4	RNA (Ribonucleic Acid)IBA 01/2021 - 07/2010
4	Monatide (IMS 3015)IBA 01/2020 - 05/2008
3	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2022 - 11/2008
3	COVID-19 VaccinesIBA 01/2022 - 01/2021
3	Protein Subunit VaccinesIBA 01/2021 - 12/2002
3	poly ICLCIBA 01/2020 - 12/2012
3	EnzymesIBA 10/2013 - 03/2004
3	HLA-A2 Antigen (HLA A2 Antigen)IBA 11/2007 - 09/2002
2	Ferritins (Ferritin)IBA 06/2020 - 01/2020
2	fibrin fragment D (D-dimer)IBA 06/2020 - 01/2020
2	ParaffinIBA 01/2019 - 12/2003
2	Immunologic Adjuvants (Immunologic Adjuvant)IBA 03/2015 - 11/2008
2	HLA-DPB1 antigen (HLA DPB1)IBA 04/2014 - 11/2004
2	AutoantigensIBA 12/2012 - 02/2009
2	CTLA-4 AntigenIBA 10/2011 - 12/2008
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 04/2010 - 07/2007
2	ProteomeIBA 03/2010 - 02/2009
2	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 08/2008 - 12/2003
1	cemiplimabIBA 01/2022
1	Transforming Growth Factor-beta Type II ReceptorIBA 01/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022
1	Creatine Kinase (Creatine Phosphokinase)IBA 01/2022
1	SteroidsIBA 01/2022
1	IgG Receptors (Fc gamma RI)IBA 01/2022
1	mRNA VaccinesIBA 12/2021
1	Celecoxib (Celebrex)FDA Link 07/2021
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 07/2021
1	Small Cytoplasmic RNAIBA 01/2021
1	Mitogen-Activated Protein KinasesIBA 01/2021
1	Monophenol Monooxygenase (Tyrosinase)IBA 01/2021

Therapy/Procedure

47	Immunotherapy 01/2022 - 09/2002
25	Therapeutics 01/2022 - 02/2009
6	Drug Therapy (Chemotherapy) 01/2018 - 02/2007
3	Radiotherapy 12/2018 - 03/2012
2	Injections 04/2016 - 03/2015
2	Stem Cell Transplantation 06/2014 - 02/2007
1	Immunomodulation 06/2022
1	Duration of Therapy 01/2022
1	Transplantation 10/2021
1	Intradermal Injections 07/2021